Why metformin is not suitable for treating obesity
Metformin is best known as a treatment for type 2 diabetes and has other potential benefits, but it is not approved for weight loss.
Metformin Effects:
◦ Improves blood sugar control: It lowers blood sugar levels and improves insulin resistance in people with type 2 diabetes.
Weight management: It can help induce gradual weight loss and also suppresses appetite.
◦ Reduced risk of cardiovascular disease: May reduce the risk of heart attack and stroke.
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Here are some reasons why metformin is not recommended for weight loss:
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Off-label use issues:
Metformin is approved as a treatment for type 2 diabetes, but is not approved as a treatment for obesity. Since it is not approved for use by the U.S. Food and Drug Administration (FDA) or Japan, there is insufficient medical evidence.
Risk of Side Effects:
Gastrointestinal side effects are common, with diarrhea being relatively common, but nausea, abdominal pain, and abdominal bloating have also been reported.
◦ There is a risk of vitamin B12 deficiency.
◦There is also a rare risk of a serious side effect called lactic acidosis.
Many people experience such severe side effects that they stop taking the drug.
Weight loss results vary greatly from person to person:
Studies have shown that the average weight loss is around 2-4.5kg, but this varies widely from person to person and may not work for everyone, especially if combined with lifestyle changes.
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